منابع مشابه
Neuropilin-2, a Novel Member of the Neuropilin Family, Is a High Affinity Receptor for the Semaphorins Sema E and Sema IV but Not Sema III
Semaphorins are a large family of secreted and transmembrane proteins, several of which are implicated in repulsive axon guidance. Neuropilin (neuropilin-1) was recently identified as a receptor for Collapsin-1/Semaphorin III/D (Sema III). We report the identification of a related protein, neuropilin-2, whose mRNA is expressed by developing neurons in a pattern largely, though not completely, n...
متن کاملThe Transmembrane Semaphorin Sema I Is Required in Drosophila for Embryonic Motor and CNS Axon Guidance
The semaphorins comprise a large family of conserved glycoproteins, several members of which have been shown to function in repulsive neuronal growth cone guidance. We show here that Drosophila Semaphorin I (Sema I), a transmembrane semaphorin expressed on embryonic motor and CNS axons, is required for correct guidance of motor axons and for the formation of CNS pathways. In mutant embryos lack...
متن کامل2 SELMAN AKBULUT AND SEMA SALUR Alternatively
Here we study the deformations of associative submanifolds inside a G 2 manifold M 7 with a calibration 3-form ϕ. A choice of 2-plane field Λ on M (which always exits) splits the tangent bundle of M as a direct sum of a 3-dimensional associate bundle and a complex 4-plane bundle T M = E ⊕ V, and this helps us to relate the deformations to Seiberg-Witten type equations. Here all the surveyed res...
متن کاملPlexinA1 Autoinhibition by the Plexin Sema Domain
Semaphorin 3A (Sema3A) binds to neuropilin-1 (NP1) and activates the transmembrane Plexin to transduce a repulsive axon guidance signal. Here, we show that Sema3 signals are transduced equally effectively by PlexinA1 or PlexinA2, but not by PlexinA3. Deletion analysis of the PlexinA1 ectodomain demonstrates that the sema domain prevents PlexinA1 activation in the basal state. Sema-deleted Plexi...
متن کاملSEMA 4 D ( sema domain , immunoglobulin domain ( Ig ) , transmembrane domain ( TM ) and short cytoplasmic domain , ( semaphorin ) 4 D )
Note Semaphorin 4D (Sema4D) was originally identified by Hall., et al. (1996) as a cell surface protein important in B and T lymphocyte activation. Its expression is upregulated in lymphocytes in an immune response (Kumanogoh et al., 2000; Wang et al., 2001). Sema 4D is also expressed in other tissues where it is involved in many motility responses (for review: Artigiani et al., 1999), includin...
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ژورنال
عنوان ژورنال: Ankara Üniversitesi İlahiyat Fakültesi Dergisi
سال: 1954
ISSN: 1301-0522
DOI: 10.1501/ilhfak_0000000407